Throughout the history of mankind, the brain and the concept of consciousness have perplexed even the greatest minds. Yet even today and throughout the technological revolution, great minds are still seeking answers to this enigmatic organ’s functions and foundation. The brain has a long history of inquisitive intellectuals attempting to describe that which has long eluded mankind; a history that dates back to the earliest human civilizations.
Greek philosopher Herophilus was first in recorded history to propose that the brain was the center of intellect, although the view was not widely accepted, and the following century, Roman physicians concluded that mental activity occurred in the brain rather than in the heart as previously thought (Saladin, 2010, 515). Brain and bodily dissections became increasingly ubiquitous during the Renaissance and incredibly, Leonardo de Vinci dissected and drew numerous, extremely detailed and anatomically correct examples as seen in figure one (Schwartz, 2002, 31). During these early centuries, dissections of the body and brain exposed a system of canals and compartments that seemed empty within the cadaver’s brain. These compartments were believed to contain the surreptitious human spirit, or the soul. Thus the brain was believed to be the seat of intelligence as well as contain the human spirit, but the roles of specific areas within the brain were far from discovery.

Figure 1. Da Vinci, Leonardo. “Central Nervous System.” History of the Brain. Web. Accessed November 30, 2010.
Nicolaus Steno and Thomas Willis rocked the foundations of brain anatomy in the 17th century by demonstrating that the ‘house’ of the human spirit did not actually exist within the brain, but that the brain was a complete organ with its own specialized system of circulation. Previous beliefs suggested that what we now recognize as the lateral ventricles of the brain were actually houses for the spirit; Steno and Willis disproved this theory through experiments utilizing henna and demonstrating the flow of cerebro-spinal fluid through these areas (Saladin, 2010, 516). Yet even incorporating these incredible discoveries, the true brain revolution began with the invention of the modern microscope. But where exactly are neuro-scientists in their ever-present search to describe the mystery of human consciousness?
Modern scientists have long described the verified anatomy of the brain and descriptions of the numerous cells that compose the intricacies of this mysterious organ. They have also characterized various ways in which this enigmatic organ can become diseased and verified that our brain communicates via chemical and electrical signals. Furthermore, neuro-scientists have determined the process by which neurons ‘fire,’ the underlying mechanism of thought and action: A neuron creates electrical potentials that travel along the axon of that neuron until the signal reaches a synapse, or the meeting of two neurons. After releasing neuron-specific chemical signals, also known as neurotransmitter, across the synaptic cleft, the neurotransmitter binds to receptors on the next neuron and that neuron becomes excited. Thus continuing the cycle of electrical potentials until a thought or action occurs from the signaled instructions.









Neurons have been found to make decisions ten-seconds before we are conscious of that decision (Smith, 2008, 1), that a vital component of long-term memory includes long-term potentiation of neurons and the numerous areas involved in the process and storage of memories (Saladin, 2010, 538-39). We have discovered areas specific to understanding and interpreting written and spoken language (figure 3). We are learning about the inner-workings of the human brain to such a level that it seems preposterous to suppose that we have not discovered the precise mechanisms of human consciousness, yet it is the truth. Neuroscience has discovered that the reticular formation (found throughout the brainstem) is associated with the ability to become conscious of certain stimuli and thought and even the ability to be conscious of our body parts and ourselves, but there is no known pathway to which the model that most associate with consciousness arises. The personality, the ‘spirit,’ the ability to be conscious of the universe and humanity’s place within it as well as the mechanisms behind humanity’s ubiquitous desire to seek further knowledge are all concepts many consider vital components of consciousness. Neuroscience has designated the frontal lobe as the seat of various characteristics of personality through the accidental lobotomy of individuals and their subsequent deviations in personality, but we are no nearer to discovering the origin of our individual uniqueness in personality and preferences.

Figure 3. Hameroff, Stuart. “What is Consciousness?” The New Frontier in Brain/Mind Science, Quantum Consciousness. Web. Accessed December 5, 2010.
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Works Cited
Pinker, Steven. “The Brain: The Mystery of Consciousness.” Time Magazine Friday, January 19, 2007. http://www.time.com/time/magazine/article/0,9171,1580394-1,00.html
Saladin, Kenneth, S. “Anatomy and Physiology: The Unity of Form and Function, Fifth Edition.” New York, New York: Mc-Graw-Hill Companies Inc, 2010. Print.
Schwartz, Jeffrey. “The Mind and the Brain.” New York, New York: HarperCollins Publishers Inc. 2002. Print.
Smith, Kerri. “Brain makes decisions before you even know it.” Nature News. April 11, 2008. http://www.nature.com/news/2008/080411/full/news.2008.751.html
Vuilleumier, Patrik, Armony, Jorge L., Driver, Jon, Dolan Raymond J. “Effects of Attention and Emotion on Face Processing in the Human Brain: An Event-Related fMRI Study.” Neuron 30:3, June, 2001, 829-841.
Figure 1. Da Vinci, Leonardo. “Central Nervous System.” History of the Brain. Web. Accessed November 30, 2010.
Figure 2. Saladin, Kenneth, S. “Anatomy and Physiology: The Unity of Form and Function, Fifth Edition.” New York, New York: Mc-Graw-Hill Companies Inc, 2010. Print.
(labeling by self)
Figure 3. Hameroff, Stuart. “What is Consciousness?” The New Frontier in Brain/Mind Science, Quantum Consciousness. Web. Accessed December 5, 2010.
